RENAL L-2-HYDROXYGLUTARATE DEHYDROGENASE ACTIVITY PROMOTES HYPOXIA TOLERANCE AND MITOCHONDRIAL METABOLISM IN DROSOPHILA MELANOGASTER

Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster

Objectives: The mitochondrial enzyme L-2-hydroxyglutarate dehydrogenase (L2HGDH) regulates the abundance of L-2-hydroxyglutarate (L-2HG), a potent signaling metabolite capable of influencing chromatin architecture, mitochondrial metabolism, and cell fate decisions.Loss of L2hgdh activity in humans induces Personal Care ectopic L-2HG accumulation, r

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A Survey of Analytical Techniques for Noroviruses

As the DIY Wig Making Tool leading cause of acute gastroenteritis worldwide, human noroviruses (HuNoVs) have caused around 685 million cases of infection and nearly $60 billion in losses every year.Despite their highly contagious nature, an effective vaccine for HuNoVs has yet to become commercially available.Therefore, rapid detection and subtypin

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